Best On-Premises Pharmaceutical Manufacturing Software of 2026

The Asset Guardian (TAG) Mobi: Tackle Downtime with TAG Mobi TAG Mobi is a fully embedded preventive maintenance and asset management (EAM) solution within Microsoft Dynamics 365 Business Central. Designed for modern manufacturing and infrastructure operations, TAG Mobi helps reduce risk, minimize downtime, and streamline maintenance workflows—all from within your existing Business Central environment. From proactive asset health monitoring and predictive maintenance to real-time mobility and AI-powered adoption tools, TAG Mobi equips maintenance teams with everything they need to boost performance and take control of asset operations. Key Features: • Fully embedded in Microsoft Dynamics 365 Business Central • Real-time mobile access for on-the-go asset tracking • Predictive maintenance to reduce unplanned downtime • AI-assisted onboarding for faster adoption • Advanced APM tools to monitor asset health and anticipate failures No silos. No extra software. Just a seamless, native experience that empowers maintenance teams and provides managers with the insights they need—right inside Business Central.

QT9 ERP helps manufacturers in regulated industries simplify production, inventory, and compliance with one connected, validated platform. Seamlessly integrating with QT9 QMS, it delivers real-time visibility, end-to-end traceability, and automated FDA and ISO compliance. Available cloud-based or on-premise, QT9 ERP includes built-in validation, configurable workflows, and unlimited support to help teams reduce errors, boost efficiency, and stay audit-ready.

Sarjen’s Manufacturing Process Automation solution brings true digital transformation to the shop floor by embedding AI at the core of every operation. It is not just about replacing paper with screens; it is about enabling systems to think, learn, and continuously improve. AI captures real-time production data from machines, operators, and quality checkpoints, turning raw information into actionable intelligence. It detects deviations instantly, predicts potential failures before they disrupt production, and recommends corrective actions to prevent costly downtime. With intelligent pattern recognition, AI strengthens quality control by identifying anomalies that manual reviews often miss. It reduces human errors, streamlines batch execution, and ensures every step aligns with regulatory and compliance standards. Predictive analytics optimize resource utilization, improve yield, and balance workloads dynamically. Instead of reactive decision-making, teams gain proactive insights that drive faster, smarter responses. AI-powered automation also enhances traceability and transparency, creating a connected manufacturing ecosystem where data flows seamlessly across systems. This level of intelligence accelerates release cycles, improves operational efficiency, and builds resilience in highly regulated industries like pharmaceuticals and life sciences. By combining automation with advanced AI capabilities, organizations move beyond incremental improvements and achieve sustainable, scalable transformation in manufacturing performance.

BatchMaster Manufacturing ERP Solutions can be used by formula-based process manufacturers in the Food, Chemical, Nutraceutical, and Life Sciences industries. Our software supports batch production, formulation, packaging management, batch production, quality and recall, lot traceability & rappel, industry-specific compliance, planning, scheduling, mobile warehousing, and other process manufacturing functions. Manufacturers can use their existing financial systems to run our process manufacturing application, including QuickBooks, Sage 100&300 and Microsoft Dynamics GP. We offer an ERP solution for manufacturers looking to replace or upgrade existing business systems. It supports specific manufacturing, financials and sales as well as supply chain, purchasing and customer service. Our applications are available on-premise (purchased), and in the cloud (monthly subscription programs).

The AssurX platform is a powerful software platform for enterprise quality management (EQMS) and regulatory compliance to reliably communicate and coordinate information, documentation, and activities. AssurX allows regulated businesses to quickly identify and control quality issues and risk exposure to avoid quality or noncompliance problems while improving workflow. AssurX QMS software is uniquely configurable to fit any established or dynamic business requirements. The system creates an electronic workflow of tasks, alerts, escalations, and approvals that can be automated to the desired level, mapping precisely to real-world operations. No other system is easier to deploy, configure, and modify. AssurX solutions integrate seamlessly to create a connected quality system. Solutions include audit management, corrective actions, training management, compliant management, document management, change control, risk management, EHS incident management, and more.

TrendMiner is an advanced industrial analytics platform that is fast, powerful, and intuitive. It was designed to monitor and troubleshoot industrial processes in real-time. It allows for robust data collection, analysis and visualization, allowing everyone in industrial operations to make smarter data-driven decision efficiently. TrendMiner is a Proemion Company founded in 2008. Our global headquarters are located in Belgium and we have offices in the U.S.A., Germany, Spain, and the Netherlands. TrendMiner has strategic alliances with major players like Amazon, Microsoft and SAP. It also offers standard integrations for a variety of historians, including Honeywell PHD and GE Proficy Historian.

Mareana, a cloud-based Enterprise AI Platform, connects siloed data in manufacturing and enables contextualization, processing and predictive analytics in real-time to drive insightful business decision. Mareana Manufacturing Intelligence is a powerful tool that helps small, large, and medium-sized enterprises increase yield, unlock capital, and comply with regulatory requirements. The Mareana Intelligence Platform offers the following benefits: - Connect your data in one place, such as paper batch records, CMO process data, and unstructured data - Create Product Generatives in Real-Time, and get Granular Product Details, Process Anomalies and Variations, as well as New Data Impact Analytics - Unlock Capital by releasing On Hold Batches, Improving yield, and reducing Up-stream/Down-stream Non-Conformances - Execute Compliance Files Flawlessly, by ensuring full reporting, leveraging data sources and reducing errors. Three of the top ten pharmaceutical companies in the US use Mareana's platform for CPV & CMC.